Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa
Identifieur interne : 000956 ( Main/Exploration ); précédent : 000955; suivant : 000957Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa
Auteurs : Pascale Chaillet [Belgique] ; Katie Tayler-Smith [Luxembourg (pays)] ; Rony Zachariah [Luxembourg (pays)] ; Nanfack Duclos ; Diallo Moctar ; Greet Beelaert [Belgique] ; Katrien Fransen [Belgique]Source :
- Transactions of The Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2010-09.
English descriptors
- KwdEn :
Abstract
With both HIV-1 and HV-2 prevalent in Guinea-Conakry, accurate diagnosis and differentiation is crucial for treatment purposes. Thus, four rapid HIV tests were evaluated for their HIV-1 and HIV-2 diagnostic and discriminative capacity for use in Guinea-Conakry. These included SD Bioline HIV 1/2 3.0 (Standard Diagnostics Inc.), Genie II HIV1/HIV2 (Bio-Rad), First Response HIV Card Test 1–2.0 (PMC Medical) and Immunoflow HIV1-HIV2 (Core Diagnostics). Results were compared with gold standard tests (INNO-LIA HIV-I/II Score) and NEW LAV BLOT II (Bio-Rad). Four hundred and forty three sequential stored HIV-positive serum samples, of known HIV-type, were evaluated. Genie II HIV1/HIV2, Immunoflow HIV1-HIV2 and SD Bioline HIV 1/2 3.0 had 100% sensitivity (95% CI, 98.9–100%) while for First Response HIV Card Test 1–2.0 this was 99.5% (95% CI, 98.2%-99.9%). In terms of discriminatory capacity, Genie II HIV1/HIV2 identified 382/ 384(99.5%) HIV-1 samples, 49/ 52(95%) HIV-2 and 7/7(100%) HIV-positive untypable samples. Immunoflow HIV1-HIV2 identified 99% HIV-1, 67% HIV-2 and all HIV-positive untypable samples. First Response HIV Card Test 1–2.0 identified 94% HIV-1, 64% HIV-2 and 57% HIV-positive untypable samples. SD-Bioline HIV 1/2 3.0 was the worst overall performer identifying 65% HIV-1, 69% HIV-2 and all HIV-positive untypable samples. The use of SD Bioline HIV 1/2 3.0 (the current standard in Guinea-Conakry) as a discriminatory HIV test is poor and may be best replaced by Immunoflow HIV1-HIV2.
Url:
DOI: 10.1016/j.trstmh.2010.05.007
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000315
- to stream Istex, to step Curation: 000315
- to stream Istex, to step Checkpoint: 000124
- to stream Main, to step Merge: 000963
- to stream Main, to step Curation: 000956
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa</title><author><name sortKey="Chaillet, Pascale" sort="Chaillet, Pascale" uniqKey="Chaillet P" first="Pascale" last="Chaillet">Pascale Chaillet</name></author><author><name sortKey="Tayler Smith, Katie" sort="Tayler Smith, Katie" uniqKey="Tayler Smith K" first="Katie" last="Tayler-Smith">Katie Tayler-Smith</name></author><author><name sortKey="Zachariah, Rony" sort="Zachariah, Rony" uniqKey="Zachariah R" first="Rony" last="Zachariah">Rony Zachariah</name></author><author><name sortKey="Duclos, Nanfack" sort="Duclos, Nanfack" uniqKey="Duclos N" first="Nanfack" last="Duclos">Nanfack Duclos</name></author><author><name sortKey="Moctar, Diallo" sort="Moctar, Diallo" uniqKey="Moctar D" first="Diallo" last="Moctar">Diallo Moctar</name></author><author><name sortKey="Beelaert, Greet" sort="Beelaert, Greet" uniqKey="Beelaert G" first="Greet" last="Beelaert">Greet Beelaert</name></author><author><name sortKey="Fransen, Katrien" sort="Fransen, Katrien" uniqKey="Fransen K" first="Katrien" last="Fransen">Katrien Fransen</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CC5ABE94DEB0801570E4CF9CDB8DEDD274064795</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1016/j.trstmh.2010.05.007</idno><idno type="url">https://api.istex.fr/document/CC5ABE94DEB0801570E4CF9CDB8DEDD274064795/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000315</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000315</idno><idno type="wicri:Area/Istex/Curation">000315</idno><idno type="wicri:Area/Istex/Checkpoint">000124</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000124</idno><idno type="wicri:doubleKey">0035-9203:2010:Chaillet P:evaluation:of:four</idno><idno type="wicri:Area/Main/Merge">000963</idno><idno type="wicri:Area/Main/Curation">000956</idno><idno type="wicri:Area/Main/Exploration">000956</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa</title><author><name sortKey="Chaillet, Pascale" sort="Chaillet, Pascale" uniqKey="Chaillet P" first="Pascale" last="Chaillet">Pascale Chaillet</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Médecins sans Frontiérès, Medical Department, Brussels Operational Center, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Tayler Smith, Katie" sort="Tayler Smith, Katie" uniqKey="Tayler Smith K" first="Katie" last="Tayler-Smith">Katie Tayler-Smith</name><affiliation wicri:level="1"><country xml:lang="fr">Luxembourg (pays)</country><wicri:regionArea>Médecins sans Frontiérès, Medical Department, Brussels Operational Center</wicri:regionArea><wicri:noRegion>Brussels Operational Center</wicri:noRegion></affiliation></author><author><name sortKey="Zachariah, Rony" sort="Zachariah, Rony" uniqKey="Zachariah R" first="Rony" last="Zachariah">Rony Zachariah</name><affiliation wicri:level="1"><country xml:lang="fr">Luxembourg (pays)</country><wicri:regionArea>Médecins sans Frontiérès, Medical Department, Brussels Operational Center</wicri:regionArea><wicri:noRegion>Brussels Operational Center</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Luxembourg (pays)</country></affiliation></author><author><name sortKey="Duclos, Nanfack" sort="Duclos, Nanfack" uniqKey="Duclos N" first="Nanfack" last="Duclos">Nanfack Duclos</name><affiliation><wicri:noCountry code="subField">Africa</wicri:noCountry></affiliation></author><author><name sortKey="Moctar, Diallo" sort="Moctar, Diallo" uniqKey="Moctar D" first="Diallo" last="Moctar">Diallo Moctar</name><affiliation><wicri:noCountry code="subField">Africa</wicri:noCountry></affiliation></author><author><name sortKey="Beelaert, Greet" sort="Beelaert, Greet" uniqKey="Beelaert G" first="Greet" last="Beelaert">Greet Beelaert</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Institute of Tropical Medicine, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation></author><author><name sortKey="Fransen, Katrien" sort="Fransen, Katrien" uniqKey="Fransen K" first="Katrien" last="Fransen">Katrien Fransen</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Institute of Tropical Medicine, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Transactions of The Royal Society of Tropical Medicine and Hygiene</title><title level="j" type="abbrev">Trans R Soc Trop Med Hyg</title><idno type="ISSN">0035-9203</idno><idno type="eISSN">1878-3503</idno><imprint><publisher>Royal Society of Tropical Medicine and Hygiene</publisher><date type="published" when="2010-09">2010-09</date><biblScope unit="volume">104</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="571">571</biblScope><biblScope unit="page" to="576">576</biblScope></imprint><idno type="ISSN">0035-9203</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0035-9203</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Guinea-Conakry</term><term>HIV-1</term><term>HIV-2</term><term>Rapid tests</term><term>discrimination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">With both HIV-1 and HV-2 prevalent in Guinea-Conakry, accurate diagnosis and differentiation is crucial for treatment purposes. Thus, four rapid HIV tests were evaluated for their HIV-1 and HIV-2 diagnostic and discriminative capacity for use in Guinea-Conakry. These included SD Bioline HIV 1/2 3.0 (Standard Diagnostics Inc.), Genie II HIV1/HIV2 (Bio-Rad), First Response HIV Card Test 1–2.0 (PMC Medical) and Immunoflow HIV1-HIV2 (Core Diagnostics). Results were compared with gold standard tests (INNO-LIA HIV-I/II Score) and NEW LAV BLOT II (Bio-Rad). Four hundred and forty three sequential stored HIV-positive serum samples, of known HIV-type, were evaluated. Genie II HIV1/HIV2, Immunoflow HIV1-HIV2 and SD Bioline HIV 1/2 3.0 had 100% sensitivity (95% CI, 98.9–100%) while for First Response HIV Card Test 1–2.0 this was 99.5% (95% CI, 98.2%-99.9%). In terms of discriminatory capacity, Genie II HIV1/HIV2 identified 382/ 384(99.5%) HIV-1 samples, 49/ 52(95%) HIV-2 and 7/7(100%) HIV-positive untypable samples. Immunoflow HIV1-HIV2 identified 99% HIV-1, 67% HIV-2 and all HIV-positive untypable samples. First Response HIV Card Test 1–2.0 identified 94% HIV-1, 64% HIV-2 and 57% HIV-positive untypable samples. SD-Bioline HIV 1/2 3.0 was the worst overall performer identifying 65% HIV-1, 69% HIV-2 and all HIV-positive untypable samples. The use of SD Bioline HIV 1/2 3.0 (the current standard in Guinea-Conakry) as a discriminatory HIV test is poor and may be best replaced by Immunoflow HIV1-HIV2.</div></front></TEI><affiliations><list><country><li>Belgique</li><li>Luxembourg (pays)</li></country><region><li>Région de Bruxelles-Capitale</li></region><settlement><li>Bruxelles</li></settlement></list><tree><noCountry><name sortKey="Duclos, Nanfack" sort="Duclos, Nanfack" uniqKey="Duclos N" first="Nanfack" last="Duclos">Nanfack Duclos</name><name sortKey="Moctar, Diallo" sort="Moctar, Diallo" uniqKey="Moctar D" first="Diallo" last="Moctar">Diallo Moctar</name></noCountry><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Chaillet, Pascale" sort="Chaillet, Pascale" uniqKey="Chaillet P" first="Pascale" last="Chaillet">Pascale Chaillet</name></region><name sortKey="Beelaert, Greet" sort="Beelaert, Greet" uniqKey="Beelaert G" first="Greet" last="Beelaert">Greet Beelaert</name><name sortKey="Fransen, Katrien" sort="Fransen, Katrien" uniqKey="Fransen K" first="Katrien" last="Fransen">Katrien Fransen</name></country><country name="Luxembourg (pays)"><noRegion><name sortKey="Tayler Smith, Katie" sort="Tayler Smith, Katie" uniqKey="Tayler Smith K" first="Katie" last="Tayler-Smith">Katie Tayler-Smith</name></noRegion><name sortKey="Zachariah, Rony" sort="Zachariah, Rony" uniqKey="Zachariah R" first="Rony" last="Zachariah">Rony Zachariah</name><name sortKey="Zachariah, Rony" sort="Zachariah, Rony" uniqKey="Zachariah R" first="Rony" last="Zachariah">Rony Zachariah</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaGhanaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000956 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000956 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaGhanaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:CC5ABE94DEB0801570E4CF9CDB8DEDD274064795
|texte= Evaluation of four rapid tests for diagnosis and differentiation of HIV-1 and HIV-2 infections in Guinea-Conakry, West Africa
}}
| This area was generated with Dilib version V0.6.31. |  |